The major hurdleslack of objective diagnostic biomarkers, the BBB impeding drug delivery, significant patient heterogeneity, and the need for more sensitive clinical trial endpointscollectively form a critical barrier to progress
Their role in supporting elderly people in their own homes and in preventing handicap is largely undervalued -and unmeasured
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En estos estudios, a los sujetos se les administr de 1500 a 3000 mg de acetil-L-carnitina diariamente durante un perodo de 3 a 12 meses
Of these, two meta-analyses found a statistically significant mortality benefit [36,41], five did not discuss mortality [33,34,39,42,43], and eleven failed to find a significant mortality reduction [35,37,38,40,4449,66]
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